Invitrogen™ TCF12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5112083

Catalog No. PIPA5112083

Description

This antibody reacts with: Human, Mouse, Rat (Species predicted to react based on 100% sequence homology).

TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.

Specifications

• Antigen: TCF12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TCF12
• Gene Alias: A130037E08Rik; ALF1; bHLHb20; Class A helix-loop-helix transcription factor ME1; class B basic helix-loop-helix protein 20; CRS3; DNA-binding protein HTF4; E-box-binding protein; HEB; HEBAlt; helix-loop-helix transcription factor 4; HsT17266; HTF4; HTF-4; ME1; Meb; REB; Salivary-specific cAMP response element-binding protein alpha; SCBP alpha; SCBPA; SCBP-alpha; TCF12; TCF-12; Transcription factor 12; transcription factor HTF-4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 6938
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.03% ProClin 300; pH 7
• Gene Accession No.: Q99081
• Gene Symbols: TCF12
• Immunogen: A synthetic peptide corresponding to the N-terminus of the Human TCF12.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov