Invitrogen™ TCF19 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110468

Catalog No. PIPA5110468

Description

Immunogen sequence: MLPCFQLLRI GGGRGGDLYT FHPPAGAGCT YRLGHRADLC DVALRPQQEP GLISGIHAEL HAEPRGDDWR VSLEDHSSQG TLVNNVRLPR GHRLELSDGD LLTFGPEGPP GTSPSEFYFM FQQVRVKPQD FAAITIPRSR GEARVGAGFR PMLPSQGAPQ RPLSTFSPAP KATLILNSIG SLSKLRPQPL TFSPSWGGPK SLPVPAPPGE MGTTPSAPPQ RNRRKSVHRV LAELDDESEP PENPPPVLME PRKKLRVDKA PLTPTGNRRG RPRKYPVSAP MAPPAVGGGE.

TCF-19 (transcription factor 19), also known as SC1 or SC1-1, is a 345 amino acid protein that contains one FHA domain, a proline-rich domain and one PHD-type zinc finger. Localizing to the nucleus, TCF-19 is a growth regulated protein that is believed to function as a trans-activating factor with a role in the transcription of genes involved in the late stages of cell cycle progression (G1 to S transition or entry of cells into G2 and mitosis). TCF-19 is expressed preferentially in the G1-S phase of the cell cycle. The gene encoding TCF-19 localizes to a critical region on chromosome 6 that has been associated with psoriasis vulgaris, a disorder of the skin that is characterized by hyperproliferation of epidermal cells. This suggests that TCF-19, via its regulation of late cell cycle-specific genes, may play a role in the development of this disorder.

Specifications

• Antigen: TCF19
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TCF19
• Gene Alias: 5730403J10Rik; AW495861; DAMA-213L4.5; SC 1; SC1; SC1 protein homolog; SC1(TCF19)-6; SC1(TCF19)-7; SC1-1; SCI(TCF19)-4; TCF 19; TCF19; TCF-19; Transcription factor 19; transcription factor 19-like protein; Transcription factor SC1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 106795, 406195, 6941
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.55 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q99KJ5, Q9Y242
• Gene Symbols: TCF19
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human TCF19 (NP_009040.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov