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Invitrogen™ TCF3 Monoclonal Antibody (6B8)
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Catalog No. PIMA515603
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100 μL
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PIMA515603 100 μL
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Catalog No. PIMA515603 Supplier Invitrogen™ Supplier No. MA515603
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Description

Mouse Monoclonal Antibody

MA5-15603 targets TCF3 in indirect ELISA, FACS and WB applications and shows reactivity with Human samples. The MA5-15603 immunogen is purified recombinant fragment of human TCF3 expressed in E. Coli. MA5-15603 detects TCF3 which has a predicted molecular weight of approximately 67.6kDa.

TCF3 (E2A) is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TCF3
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 6B8
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene TCF3
Gene Accession No. P15923
Gene Alias A1; AA408400; AGM8; Alf2; AW209082; bHLHb21; class B basic helix-loop-helix protein 21; E12; E12/E47; E2A; E47; helix-loop-helix protein HE47; immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin transcription factor 1; ITF1; Kappa-E2-binding factor; Me2; MGC129647; MGC129648; negative vitamin D response element-binding protein; NOL1-TCF3 fusion; Pan; Pan1; Pan2; pancreas specific transcription factor 1c; Ptf1c; TCF3; TCF-3; Tcfe2a; Transcription factor 3; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); transcription factor 3 variant 3; transcription factor A1; transcription factor E2a; Transcription factor E2-alpha; transcription factor ITF-1; Transcription regulator Pan; VDIR; VDR interacting repressor; vitamin D receptor-interacting repressor
Gene Symbols TCF3
Host Species Mouse
Immunogen Purified recombinant fragment of human TCF3 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6929
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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