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Invitrogen™ TCF3 Polyclonal Antibody
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Catalog No. PIPA584553
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100 μL
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PIPA584553 100 μL
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Catalog No. PIPA584553 Supplier Invitrogen™ Supplier No. PA584553
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LAGSTSLMHN HAALPSQPGT LPDLSRPPDS YSGLGRAGA Highest antigen sequence indentity to the following orthologs: Mouse - 75%, Rat - 73%.

TCF3 (E2A) is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TCF3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TCF3
Gene Accession No. P15923
Gene Alias A1; AA408400; AGM8; Alf2; AW209082; bHLHb21; class B basic helix-loop-helix protein 21; E12; E12/E47; E2A; E47; helix-loop-helix protein HE47; immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin transcription factor 1; ITF1; Kappa-E2-binding factor; Me2; MGC129647; MGC129648; negative vitamin D response element-binding protein; NOL1-TCF3 fusion; Pan; Pan1; Pan2; pancreas specific transcription factor 1c; Ptf1c; TCF3; TCF-3; Tcfe2a; Transcription factor 3; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); transcription factor 3 variant 3; transcription factor A1; transcription factor E2a; Transcription factor E2-alpha; transcription factor ITF-1; Transcription regulator Pan; VDIR; VDR interacting repressor; vitamin D receptor-interacting repressor
Gene Symbols TCF3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TCF3. Recombinant protein control fragment (Product #RP-103451).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6929
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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