Invitrogen™ TCF3/TCF4 Monoclonal Antibody (6F12-3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA125418

Catalog No. PIMA125418

Description

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

TCF 4 (T cell factor 4) is a member of the TCF/LEF (lymphoid enhancer factor) family of transcription factors. Members of this family along with b catenin, are involved in mediating Wnt signaling by transactivating downstream genes. TCF 4 generates transcriptionally active complexes with b catenin in colon carcinoma cells. Expression of TCF 4 is highest in the CNS and intestinal epithelium where Wnt signaling also plays an essential role in development. Aberrant TCF 4 transcription activity has been implicated in carcinogenesis of intestinal and mammary epithlia.

Specifications

• Antigen: TCF3/TCF4
• Classification: Monoclonal
• Concentration: 0.53 mg/mL
• Formulation: TBS with 30% glycerol and 0.08% sodium azide; pH 7.4
• Gene Accession No.: P15806, P15884, P15923, Q60722
• Gene Symbols: TCF3, Tcf4
• Immunogen: His-tagged fusion protein corresponding to residues 31-331 of human TCF4.
• Quantity: 25 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 6F12-3
• Conjugate: Unconjugated
• Gene: Tcf4
• Gene Alias: 5730422P05Rik; A1; AA408400; AGM8; ALF2; ASP-I2; AW209082; bHLHb19; BHLHB21; Class A helix-loop-helix transcription factor ME2; class B basic helix-loop-helix protein 19; Class B basic helix-loop-helix protein 21; E12; E12/E47; E2.2; E2-2; E2A; E47; FECD3; helix-loop-helix protein HE47; immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin transcription factor 1; immunoglobulin transcription factor 2; immunoglobulin transcription factor-2; ITF1; ITF-1; ITF2; ITF-2; ITF-2b; kappa-E2-binding factor; Me2; MITF-2; MITF-2A; MITF-2B; negative vitamin D response element-binding protein; NOL1-TCF3 fusion; Pan1; Pan2; PTHS; SEF2; SEF-2; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; SL3-3 enhancer factor 2; Tcf3; TCF-3; TCF4; TCF-4; Tcfe2a; TFE; Transcription factor 3; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); transcription factor 3 variant 3; transcription factor 4; Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2); transcription factor 4, isoform C; transcription factor 4, isoform D; transcription factor 4, isoform E; transcription factor 4, isoform L; transcription factor 4, isoform M; transcription factor 4, isoform R; transcription factor A1; transcription factor E2a; Transcription factor E2-alpha; transcription factor ITF-1; VDIR; VDR interacting repressor; vitamin D receptor-interacting repressor
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 21413, 21423, 6925, 6929
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid