Invitrogen™ TCF4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577796

Catalog No. PIPA577796

Description

A 1:1,000 dilution of PA5-77796 was sufficient for detection of TCF4 in 15 μg of mouse liver cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. Detects 71 kDa, 45 kDa. 45 kDa band represents a different isoform .

TCF4 is transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG')-a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome.

Specifications

• Antigen: TCF4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TCF4
• Gene Alias: 5730422P05Rik; ASP-I2; bHLHb19; class A helix-loop-helix transcription factor ME2; Class B basic helix-loop-helix protein 19; E2 2; E2.2; E2-2; FECD3; Immunoglobulin transcription factor 2; immunoglobulin transcription factor-2; ITF 2; ITF2; ITF-2; ITF-2b; ME2; MGC149723; MGC149724; MITF-2; MITF-2A; MITF-2B; PTHS; R8f DNA-binding protein; RITF-2; SEF 2; SEF2; SEF-2; SEF2 1; SEF2 1A; SEF2 1B; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; SL3-3 enhancer factor 2; TCF 4; TCF4; TCF-4; TFE; Transcription factor 4; Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2); transcription factor 4, isoform C; transcription factor 4, isoform D; transcription factor 4, isoform E; transcription factor 4, isoform L; transcription factor 4, isoform M; transcription factor 4, isoform R
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21413, 6925
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P15884, Q60722
• Gene Symbols: TCF4
• Immunogen: Synthetic peptide from the C-terminal of Human TCF4 (500-600 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG