Invitrogen™ TCF4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588125

Catalog No. PIPA588125

Description

Immunogen sequence: MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV EDRSSSGSWG NGGHPSPSRN YGDGTPYDHM TSRDLGSHDN LSPPFVNSRI QSKTERGSYS SYGRESNLQG CHQQSLLGGD MDMGNPGTLS PTKPGSQYYQ YSSNNPRRRP LHSSAMEVQT KKVRKVPPGL PSSVYAPSAS TADYNRDSPG YPSSKPATST Positive Samples: A375, K-562; Cellular Location: Nucleus.

TCF4 is transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG')-a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome.

Specifications

• Antigen: TCF4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TCF4
• Gene Alias: 5730422P05Rik; ASP-I2; bHLHb19; class A helix-loop-helix transcription factor ME2; Class B basic helix-loop-helix protein 19; E2 2; E2.2; E2-2; FECD3; Immunoglobulin transcription factor 2; immunoglobulin transcription factor-2; ITF 2; ITF2; ITF-2; ITF-2b; ME2; MGC149723; MGC149724; MITF-2; MITF-2A; MITF-2B; PTHS; R8f DNA-binding protein; RITF-2; SEF 2; SEF2; SEF-2; SEF2 1; SEF2 1A; SEF2 1B; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; SL3-3 enhancer factor 2; TCF 4; TCF4; TCF-4; TFE; Transcription factor 4; Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2); transcription factor 4, isoform C; transcription factor 4, isoform D; transcription factor 4, isoform E; transcription factor 4, isoform L; transcription factor 4, isoform M; transcription factor 4, isoform R
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21413, 6925, 84382
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.95 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P15884, Q60722, Q62655
• Gene Symbols: TCF4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human TCF4 (NP_0031901).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG