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Invitrogen™ TCF7 Monoclonal Antibody (C.725.7)
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Catalog No. PIMA514965
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100 μL
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Catalog No. Quantity
PIMA514965 100 μL
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Catalog No. PIMA514965 Supplier Invitrogen™ Supplier No. MA514965
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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with LEF1.

TCF7 (transcriptional factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ and CD8+ immature thymocytes. Isoforms for TCF7 lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. TCF7 binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. It may also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3, and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TCF7
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone C.725.7
Concentration 100 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 0.15M NaCl, 50% glycerol, 100 μg/mL BSA and <0.02% sodium azide, pH 7.5
Gene TCF7
Gene Accession No. P36402, Q00417
Gene Alias AI465550; HMG-box; OTTHUMP00000159390; OTTHUMP00000159391; T cell factor-1; T-cell factor 1; T-cell specific; T-cell-specific transcription factor 1; Tcf1; TCF-1; Tcf7; TCF-7; Transcription factor 7; transcription factor 7 (T-cell specific, HMG-box); transcription factor 7, T cell specific; transcription factor 7, T-cell specific
Gene Symbols TCF7
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region surrounding Pro96 of human TCF1 protein.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21414, 6932
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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