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TCIRG1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 126491AP150UL

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Catalog No. 50-172-8144


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Description

Description

The T-cell immune regulator 1 (TCIRG1) is the a3 subunit of the vacuolar-type proton transporting ATPase (V-ATPase), a proton pump in late endosomes and lysosomes that functions in the luminal acidification of these organelles. Genetic defects in the gene encoding this protein a responsible for a severe form of autosomal recessive osteopetrosis, a condition that leads to increased bone density, decreased bone strength, and inflammation in bone tissues. TCIRG1 is also required for the normal secretion of insulin and the bacteria-killing function of macrophages.
Specifications

Specifications

TCIRG1
Polyclonal
Unconjugated
TCIRG1
a3, Atp6i, ATP6N1C, ATP6V0A3, OC 116 kDa, OC 116kDa, OC116, OPTB1, Stv1, T cell immune regulator 1, TCIRG1, TIRC7, V ATPase 116 kDa isoform a3, Vph1
Rabbit
Antigen Affinity Chromatography
RUO
10312, 27060, 293650
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Western Blot
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q13488
TCIRG1
TCIRG1 Fusion Protein Ag3378
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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