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TCIRG1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 126491AP150UL

Description
The T-cell immune regulator 1 (TCIRG1) is the a3 subunit of the vacuolar-type proton transporting ATPase (V-ATPase), a proton pump in late endosomes and lysosomes that functions in the luminal acidification of these organelles. Genetic defects in the gene encoding this protein a responsible for a severe form of autosomal recessive osteopetrosis, a condition that leads to increased bone density, decreased bone strength, and inflammation in bone tissues. TCIRG1 is also required for the normal secretion of insulin and the bacteria-killing function of macrophages.Specifications
TCIRG1 | |
Polyclonal | |
Unconjugated | |
TCIRG1 | |
a3, Atp6i, ATP6N1C, ATP6V0A3, OC 116 kDa, OC 116kDa, OC116, OPTB1, Stv1, T cell immune regulator 1, TCIRG1, TIRC7, V ATPase 116 kDa isoform a3, Vph1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
10312, 27060, 293650 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Western Blot | |
0.19 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q13488 | |
TCIRG1 | |
TCIRG1 Fusion Protein Ag3378 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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