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Invitrogen™ TCP-1 beta Polyclonal Antibody
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Catalog No. PIPA578952
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100 μg
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PIPA578952 100 μg
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Catalog No. PIPA578952 Supplier Invitrogen™ Supplier No. PA578952
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human A549 whole cell, human RT4 whole cell, human CACO-2 whole cell, human 293T whole cell, human MCF-7 whole cell, human HEL whole cell, human Raji whole cell, human SW620 whole cell, rat brain tissue, rat spleen tissue, rat C6 whole cell, rat PC-12 whole cell, mouse brain tissue, mouse spleen tissue, mouse NIH/3T3 whole cell, mouse RAW2647 whole cell. IHC: rat gaster tissue, human testis tissue, mouse gaster tissue. ICC/IF: U20S cell, U2OS cell. Flow: U251 cell.

TCP-1 beta is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). The CCT complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the TCP-1 beta gene have been observed but not thoroughly characterized. A disease associated with TCP-1 beta protein dysfunction include epididymo-orchitis.
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Specifications

Antigen TCP-1 beta
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.01mg sodium azide
Gene CCT2
Gene Accession No. P78371, P80314, Q5XIM9
Gene Alias 99D8.1; AI528772; c-cpn; CCT; Cct1; CCT2; Ccta; CCTB; CCT-beta; chaperonin containing t-complex polypeptide 1, beta subunit; chaperonin containing t-complex polypeptide 1, subunit 2; chaperonin containing TCP1 subunit 2; chaperonin containing Tcp1, subunit 2 (beta); chaperonin subunit 2 (beta); chaperonin-containing T-complex polypeptide beta subunit; epididymis secretory sperm binding protein Li 100n; HEL-S-100n; hypothetical protein LOC505313; p63; PRO1633; T-complex protein 1 subunit beta; T-complex protein 1, beta subunit; Tcp-1; TCP-1-beta; Tp63; TRic
Gene Symbols CCT2
Host Species Rabbit
Immunogen E.coli-derived human CCT2 recombinant protein (Position: E414-C535).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10576, 12461, 299809
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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