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Invitrogen™ TCP-1 delta Polyclonal Antibody
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Catalog No. PIPA578954
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100 μg
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PIPA578954 100 μg
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Catalog No. PIPA578954 Supplier Invitrogen™ Supplier No. PA578954
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human U20S whole cell, human SW620 whole cell, human MCF-7 whole cell, rat brain tissue, rat liver tissue, mouse brain tissue, mouse liver tissue. IHC: mouse kidney tissue, rat kidney tissue, human mammary cancer tissue IHC-F: mouse brain tissue, rat brain tissue. ICC/IF: U20S cell, LOVO Cell, Neuro-2a Cell, NRK Cell, SHG-44 Cell. Flow: PC-3 cell, U251 cell, K562 cell.

The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).
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Specifications

Antigen TCP-1 delta
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide
Gene Cct4
Gene Accession No. P50991, P80315, Q7TPB1
Gene Alias 2610204B21Rik; A45; C78323; CCT4; cct4 protein; Cctd; CCT-delta; chaperonin containing t-complex polypeptide 1, delta subunit; chaperonin containing TCP1 subunit 4; chaperonin containing Tcp1, subunit 4 (delta); chaperonin subunit 4 (delta); SRB; Stimulator of TAR RNA-binding; T complex protein 1, delta; T-complex protein 1 subunit delta; TCP-1 delta; TCP-1-delta; Unknown (protein for MGC:134500); zgc:65789; zgc:77192
Gene Symbols Cct4
Host Species Rabbit
Immunogen E. coli-derived human CCT4 recombinant protein (Position: R452-R539).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10575, 12464, 29374
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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