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Invitrogen™ TCP-1 theta Polyclonal Antibody
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Catalog No. PIPA554318
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100 μL
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PIPA554318 100 μL
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Catalog No. PIPA554318 Supplier Invitrogen™ Supplier No. PA554318
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KVLTRDKRLV PGGGATEIEL AKQITSYGET CPGLEQYAIK KFAEAFEAIP RALAENSGVK ANEVISKLYA VHQEGNKNVG LDIEAEVPAV KDMLEAGILD TYLGKYWAIK LATNAAVTVL RVDQIIMAKP AGGPKPPSGK KDWDD Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

TCP-1 theta is theta subunit of the CCT (chaperonin containing TCP1 complex) chaperonin molecule which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of the newly synthesized proteins. Molecular chaperones assist in the protein folding upon ATP hydrolysis and TCP-1 theta may play a role in the assembly of the BBsome, a complex that is involved in ciliogenesis regulating transport vesicles to the cilia. Further, TCP-1 theta is also involved in the folding of actin and tubulin. The intact CCT complex is composed of eight polypeptides in a double ring structure. CCT is important within cells in the folding of the VHL tumor suppressor protein.
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Specifications

Antigen TCP-1 theta
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CCT8
Gene Accession No. P42932, P50990
Gene Alias AI132397; bdav; bette davis; C21orf112; Cct8; Cctq; CCT-theta; Chaperonin containing T-complex polypeptide 1 subunit 8; chaperonin containing TCP1 subunit 8; chaperonin containing TCP1, subunit 8 (theta); chaperonin subunit 8 (theta); D21S246; fa22h09; KIAA0002; PRED71; renal carcinoma antigen NY-REN-15; T-complex protein 1 subunit theta; TCP-1-theta; Tcpq; wu:fa22h09; zgc:56059
Gene Symbols CCT8
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TCP-1 theta. Recombinant protein control fragment (Product #RP-91816).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10694, 12469, 288305
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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