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TCP1 alpha Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982111
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50-198-2111 100 μL
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Catalog No. 50-198-2111 Supplier Bioss Supplier No. BS12292R
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Rabbit Polyclonal Antibody

The T Complex Polypeptide 1 (TCP-1) is approximately 60 kDa protein constitutively expressed in almost all eukaryotic cells, and is upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. The family of proteins termed chaperonins act to recognize and stabilize polypeptide intermediates during folding, assembly and disassembly, and share many characteristics with Heat Shock Protein 70 (HSP70) including high abundance, induction by environmental stress, and ATPase activity. The chaperonin family includes the mitochondrial HSP60, Escherichia coli GroEL, the plastid Rubisco-subunit binding protein, and the archaebacterial protein TF55. The TCP-1 sequence shows nearly 40% identity to TF55, but only minimal similarity to HSP60 and GroEL.

Specifications

Antigen TCP1 alpha
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene TCP1
Gene Accession No. P17987
Gene Alias 65 kDa antigen; AI528772; BOS_10000; c-cpn; CCT; Cct1; Ccta; CCTalpha; CCT-alpha; chaperonin-containing T-complex alpha subunit TCP1; chaperonin-containing T-complex polypeptide alpha subunit; cytosolic chaperonin containing t-complex polypeptide 1; D6S230E; p63; RCJMB04_2b5; tailless complex polypeptide 1; Tailless complex polypeptide 1A; Tailless complex polypeptide 1B; t-complex 1; t-complex polypeptide 1; t-complex protein 1; T-complex protein 1 alpha subunit-like protein; T-complex protein 1 subunit alpha; T-complex protein 1 subunit alpha A; T-complex protein 1 subunit alpha B; T-complex protein 1, alpha subunit; TCP1; Tcp-1; TCP-1-A; TCP-1-alpha; TCP-1-B; Tp63; TRiC; YD8142.13; YD8142B.04; YDR212W
Gene Symbols TCP1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human TCP1 alpha.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6950
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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