Invitrogen™ TCP1 eta Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588378

Catalog No. PIPA588378

Description

Immunogen sequence: CAGRVPEEDL KRTMMACGGS IQTSVNALSA DVLGRCQVFE ETQIGGERYN FFTGCPKAKT CTFILRGGAE QFMEETERSL HDAIMIVRRA IKNDSVVAGG GAIEMELSKY LRDYSRTIPG KQQLLIGAYA KALEIIPRQL CDNAGFDATN ILNKLRARHA QGGTWYGVDI NNEDIADNFE AFVWEPAMVR I; Positive Samples: U-87MG, A-431, HT-29, HeLa, NIH/3T3, Mouse testis, Rat testis; Cellular Location: Cytoplasm.

The TCP1 eta gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.

Specifications

• Antigen: TCP1 eta
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCT7
• Gene Alias: AA408524; AL022769; CCT7; CCTETA; CCT-eta; CCTH; Cctz; chaperonin containing t-complex polypeptide 1, eta subunit; chaperonin containing t-complex subunit eta; chaperonin containing TCP1 subunit 7; chaperonin containing Tcp1, subunit 7 (eta); chaperonin subunit 7 (eta); HIV-1 Nef interacting protein; HIV-1 Nef-interacting protein; MGC110985; NIP7-1; T-complex protein 1 subunit eta; T-complex protein 1 subunit eta, N-terminally processed; TCP1ETA; TCP-1-eta
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10574, 12468, 297406
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.08 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P80313, Q99832
• Gene Symbols: CCT7
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 310-500 of human CCT7 (NP_0064201).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG