Invitrogen™ TCR DO11.10 Monoclonal Antibody (KJ126.1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA518036

Catalog No. PIMA518036

Description

This antibody is specific for the DO-11.10 T cell receptor idiotype. The DO-11.10 TCR is specific for chicken ovalbumin (aa 323-339) in combination with I-Ad MHC class II complex. KJ1-26 has been reported to block the antigen response of the DO-11.10 T cell hybridomas in vitro.

TCR DO11 (DO11.10) is a receptor found on lymphocytes of DO11.10 transgenic mice and T-cell receptors of BALB/c-derived DO11.10 and DO11.10.24 T cell hybridomas. The DO11.10 TCR recognizes a C-terminal ovalbumin peptide (OVA 323-339) in the context of I-Ad major histocompatibility molecules. The use of antibodies against DO11.10 have proven to be instrumental in describing many of the intricate details of T cell immunity, including T cell activation, development, and function.

Specifications

• Antigen: TCR DO11.10
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P01849
• Gene Symbols: Tcra
• Immunogen: DO-11.10 T cell hybridoma.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ELISA, Flow Cytometry
• Clone: KJ126.1
• Conjugate: Unconjugated
• Gene: Tcra
• Gene Alias: D011.10; T cell receptor alpha chain; Tcra; Tcralpha
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 21473
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid