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TCR γδ Mouse anti-Human, FITC, Clone: B1, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 561995
Description
The B1 monoclonal antibody specifically binds to the γδ T cell receptor ( γδ TCR). This receptor complex consists of two disulfide-linked transmembrane glycoproteins, a γchain (45-60 kDa) and a δ subunit (40-60 kDa). The γδ TCR is associated with the signal-transducing CD3 complex. The γδ TCR is expressed by thymocytes and by peripheral T cell subsets (γδ T cells) that are located in the blood, liver, skin and various lymphoid and mucosal tissues. γδ T cells contribute to both innate and adaptive immune responses to infections and tumors. Reports suggest that γδ T cells may also play roles in antigen presentation and the regulation of autoimmune responses.
Specifications
| TCR γδ | |
| Monoclonal | |
| 0.5mg/mL | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| B1 | |
| FITC | |
| Mouse | |
| 25 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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