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TCTN2 Mouse anti-Human, Clone: OTI1C1, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF501477

Encompass_Preferred

Catalog No. 50-166-0491


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TCTN2 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN2 is not known, it is 49% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
Specifications

Specifications

TCTN2
Monoclonal
Unconjugated
TCTN2
C12orf38, JBTS24, MKS8, TECT2
Mouse
Affinity Chromatography
RUO
79867
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI1C1
PBS with 8% trehalose and no preservative; pH 7.3
Q96GX1
TCTN2
Full length human recombit protein of human TCTN2 produced in HEK293T cell.
100 μg
Primary
Human
Antibody
IgG2a
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