Learn More
TCTN2 Mouse anti-Human, Clone: OTI1C1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF501477

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
TCTN2 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN2 is not known, it is 49% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.Specifications
TCTN2 | |
Monoclonal | |
Unconjugated | |
TCTN2 | |
C12orf38, JBTS24, MKS8, TECT2 | |
Mouse | |
Affinity Chromatography | |
RUO | |
79867 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot | |
OTI1C1 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q96GX1 | |
TCTN2 | |
Full length human recombit protein of human TCTN2 produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2a |
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.