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TCTP Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985506
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50-198-5506 100 μL
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Catalog No. 50-198-5506 Supplier Bioss Supplier No. BS3578R
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Description

Rabbit Polyclonal Antibody

TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer′s disease and Down syndrome.

Specifications

Antigen TCTP
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene TPT1
Gene Accession No. P13693
Gene Alias 21 kDa polypeptide; 21 kDa polypeptide under translational control; Fortilin; Histamine-releasing factor; HRF; Lens epithelial protein; p02; p21; p23; TCTP; Tpt1; translationally regulated transcript (21 kDa); Translationally-controlled tumor protein; Trt; tumor protein, translationally-controlled 1
Gene Symbols TPT1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human TCTP.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7178
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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