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Invitrogen™ TDE1 Polyclonal Antibody
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Catalog No. PIPA599729
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PIPA599729 100 μL
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Catalog No. PIPA599729 Supplier Invitrogen™ Supplier No. PA599729
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TDE1.

TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TDE1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Serinc3
Gene Accession No. Q13530
Gene Alias AA959945; AA960047; Aigp1; AIGP-1; axotomy-induced glyco/Golgi protein 1; Axotomy-induced glycoprotein 1; DIFF33; Membrane protein TMS-1; SBBI99; Serinc3; Serine incorporator 3; TDE; TDE1; Tms1; TMS-1; tumor differentially expressed 1; tumor differentially expressed protein 1
Gene Symbols Serinc3
Host Species Rabbit
Immunogen A synthesized peptide derived from human SERINC3(Accession Q13530), corresponding to amino acid residues V372-T422.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10955
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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