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TDG Monoclonal Antibody (OTI3A12), TrueMAB™, OriGene
SDP

Catalog No. 501682177
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100 μL
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Catalog No. Quantity
50-168-2177 100 μL
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Catalog No. 50-168-2177 Supplier OriGene Supplier No. TA808511
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Description

Mouse Monoclonal Antibody

The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.

Specifications

Antigen TDG
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone OTI3A12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene TDG
Gene Accession No. Q13569
Gene Alias hTDG
Gene Symbols TDG
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 160-253 of human TDG produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6996
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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