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TDG / Thymine-DNA glycosylase Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501993396
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50-199-3396 100 μL
50-199-3397 10 μL
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Catalog No. 50-199-3396 Supplier Active Motif Supplier No. 61437
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Description

Rabbit Polyclonal Antibody

The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mis paired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.

Specifications

Antigen TDG / Thymine-DNA glycosylase
Applications Western Blot
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene TDG
Gene Accession No. P56581
Gene Alias C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; TDG; thymine DNA glycosylase; Thymine-DNA glycosylase
Gene Symbols TDG
Host Species Rabbit
Immunogen This antibody was raised against a full-length recombinant protein corresponding to mouse thymine DNA glycosylase (TDG).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21665
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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