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Invitrogen™ TDRD6 Polyclonal Antibody
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Catalog No. PIPA5140349
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100 μL
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PIPA5140349 100 μL
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Catalog No. PIPA5140349 Supplier Invitrogen™ Supplier No. PA5140349
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: VSVVHTNKIG RLDLVNAILP GLCIHCSLQG FEVPDNKNSK KMMHYFSQRT SEAAIRCEFV KFQDRWEVIL ADEHGIIADD MISRY Highest antigen sequence indentity to the following orthologs: Mouse - 68%, Rat - 67%.

Tudor domain-containing protein involved in germ cell development, more specifically the formation of chromatoid body (during spermiogenesis), Balbiani body (during oogenesis), germ plasm (upon fertilization), and for proper miRNA expression and spliceosome maturation. Essential for RNA-dependent helicase UPF1 localization to chromatoid body, for UPF1-UPF2 and UPF1-DDX4 interactions which are required for mRNA degradation, using the extended 3' UTR-triggered nonsense-mediated mRNA decay (NMD) pathway. Involved in spliceosome maturation and mRNA splicing in prophase I spermatocytes through interaction with arginine N-methyltransferase PRMT5 and symmetrically arginine dimethylated SNRPB (small nuclear ribonucleoprotein-associated protein).
TRUSTED_SUSTAINABILITY

Specifications

Antigen TDRD6
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TDRD6
Gene Accession No. O60522
Gene Alias SPATA36; Tudor Domain Containing 6
Gene Symbols TDRD6
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TDRD6. Recombinant protein control fragment (Product #RP-94961).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 221400
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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