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Invitrogen™ TECK Polyclonal Antibody
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Catalog No. PIPA576048
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PIPA576048 100 μL
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Catalog No. PIPA576048 Supplier Invitrogen™ Supplier No. PA576048
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).

Chemokines are likely to play an important role in regulating the trafficking of developing T cells within the thymus. Chemokine C-C thymus expressed chemokine (TECK), also designated chemokine ligand 25 (CCL25), small induc-ible cytokine A25, chemokine b-15 or CK b-15, is expressed predominantly in thymic dendritic cells, thymic epithelial cells and in the small intestine. TECK, a CCR9 ligand, has suppressive activity against immature subsets of myeloid progenitors which have been stimulated to proliferate by multiple growth factors. TECK delivers signals through CCR9, which is important for the nav-igation of developing thymocytes. Bone marrow pre-pro-B cells and cells capable of generating pro-B colonies in the presence of interleukin-7 and Flt-3 ligand migrate to TECK, a response lost in later stages of B cell development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TECK
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CCL25
Gene Accession No. O15444
Gene Alias A130072A22Rik; AI852536; C-C motif chemokine 25; C-C motif chemokine ligand 25; CCL25; chemokine (C-C motif) ligand 25; chemokine TECK; Ck beta-15; CKb15; Scya25; SCYA25TECKvar; small inducible chemokine 25; small inducible cytokine A25; small inducible cytokine subfamily A (Cys-Cys), member 25; small-inducible cytokine A25; Teck; TECKMGC150327; TECKvar; thymus expressed chemokine; thymus-expressed chemokine
Gene Symbols CCL25
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CCL25: 21-120.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6370
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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