Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. FEPA5144689

Invitrogen™ TEM5 Polyclonal Antibody
GREENER_CHOICE

Catalog No. FEPA5144689
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
FEPA5144689 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. FEPA5144689 Supplier Invitrogen™ Supplier No. PA5144689
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: LLRLNISGNI FSSLQPGVFD ELPALKVVDL GTEFLTCDCH LRWLLPWAQN RSLQLSEHTL CAYPSALHAQ ALGSLQEAQL CCEGALELHT HHLIPSLRQV VFQGDRLPFQ CSAS Antigen sequence identity: Mouse 89%; Rat 89%.

Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TEM5
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ADGRA2
Gene Accession No. Q96PE1
Gene Alias 8430414O08Rik; 9530074E10Rik; Adgra2; Adgra3; Adhesion G protein-coupled receptor A2; adhesion G protein-coupled receptor A3; DKFZp434C211; DKFZp434J0911; FLJ14390; G protein-coupled receptor 124; Gpr124; G-protein coupled receptor 124; KIAA1531; LOC100363275; mKIAA1531; Tem5; Tumor endothelial marker 5
Gene Symbols ADGRA2
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 158-271. Recombinant protein control fragment (Product #RP-109719).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25960
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.