Invitrogen™ Tenascin C Monoclonal Antibody (T2H5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA544004

Catalog No. PIMA544004

Description

This antibody recognizes tenascin C, a large hexametric extracellular matrix glycoprotein.

Tenascin is a high molecular weight, multifunctional, extracellular matrix glycoprotein expressed in association with mesenchymal-epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors (Erickson and Bourdon 1989). It has been described under a variety of names: cytotactin, hexabrachion protein, J1, myotendinous antigen (MI) and glioma mesenchymal extracellular matrix (GMEM). The tenascin molecule is a disulfide-linked hexamer. The expression of tenascin is associated with development and growth, both normal and pathological, whereas the distribution in normal adult tissue is restricted.

Specifications

• Antigen: Tenascin C
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 15 mM sodium azide; pH 8
• Gene Accession No.: P24821
• Gene Symbols: TNC
• Immunogen: Protein preparation from a homogenate of a human mammary tumour specimen.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: T2H5
• Conjugate: Unconjugated
• Gene: TNC
• Gene Alias: 150-225; AI528729; C130033P17Rik; cytotactin; deafness, autosomal dominant 56; DFNA56; Glioma-associated-extracellular matrix antigen; GMEM; GP; GP 150-225; hexabrachion; hexabrachion (tenascin); Hxb; JI; MGC144208; MGC144209; MGC167029; Myotendinous antigen; neuronectin; Ten; Tenascin; tenascin C; Tenascin-C; tenascin-C additional domain 1; tenascin-C isoform 14/AD1/16; TN; tnc; TN-C
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3371
• Content And Storage: 4°C, do not freeze
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov