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Invitrogen™ Tensin 3 Polyclonal Antibody
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Catalog No. PIPA563112
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100 μL
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PIPA563112 100 μL
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Catalog No. PIPA563112 Supplier Invitrogen™ Supplier No. PA563112
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HLGPFTCHKS SQNSLLSDGF GSNVGEDPQG TLVPDLGLGM DGPYERERTF GSREPKQPQP LLRKPSVSAQ MQAYGQSSYS TQTWVRQQQM VVAHQYSFAP DGEAR Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 75%.

The Tensin (Tns) family of proteins is involved in the maintenance of cellular structure by anchoring actin filaments at the focal adhesion via F-actin binding and capping activities. Tns proteins also contain a Src homology 2 (SH2) domain and have the ability to be phosphorylated, suggesting a role in signal transduction cascades. These diverse characteristics indicate that Tns proteins may be important links between the cytoskeleton and signal transduction pathways. Tns3, also known as TEM6 or TENS1, localizes to the focal adhesions of the plasma membrane. It is predominantly expressed in thyroid and placenta but can also be found in heart, liver, brain, prostate, pancreas, kidney, lung, skeletal muscle and white blood cells. Tns3 is essential for proper growth and development, as suggested by growth retardation and death in a number of Tns3-/- mice.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Tensin 3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.30 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Tns3
Gene Accession No. Q68CZ2
Gene Alias BC023928; F830010I22Rik; RGD1564174; TEM6; TENS1; TENS3; tensin 3; tensin3; tensin-3; tensin-3-like; tensin-like SH2 domain containing 1; tensin-like SH2 domain-containing 1; tensin-like SH2 domain-containing protein 1; thyroid specific PTB domain protein; TNS3; TPP; TSN3; tumor endothelial marker 6
Gene Symbols Tns3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Tensin 3. Recombinant protein control fragment (Product #RP-103213).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64759
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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