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Invitrogen™ Tensin 3 Polyclonal Antibody
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Catalog No. PIPA5116022
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100 μL
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PIPA5116022 100 μL
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Catalog No. PIPA5116022 Supplier Invitrogen™ Supplier No. PA5116022
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TENS3.

The Tensin (Tns) family of proteins is involved in the maintenance of cellular structure by anchoring actin filaments at the focal adhesion via F-actin binding and capping activities. Tns proteins also contain a Src homology 2 (SH2) domain and have the ability to be phosphorylated, suggesting a role in signal transduction cascades. These diverse characteristics indicate that Tns proteins may be important links between the cytoskeleton and signal transduction pathways. Tns3, also known as TEM6 or TENS1, localizes to the focal adhesions of the plasma membrane. It is predominantly expressed in thyroid and placenta but can also be found in heart, liver, brain, prostate, pancreas, kidney, lung, skeletal muscle and white blood cells. Tns3 is essential for proper growth and development, as suggested by growth retardation and death in a number of Tns3-/- mice.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Tensin 3
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene Tns3
Gene Accession No. Q68CZ2
Gene Alias BC023928; F830010I22Rik; RGD1564174; TEM6; TENS1; TENS3; tensin 3; tensin3; tensin-3; tensin-3-like; tensin-like SH2 domain containing 1; tensin-like SH2 domain-containing 1; tensin-like SH2 domain-containing protein 1; thyroid specific PTB domain protein; TNS3; TPP; TSN3; tumor endothelial marker 6
Gene Symbols Tns3
Host Species Rabbit
Immunogen A synthesized peptide derived from human TNS3(Accession Q68CZ2), corresponding to amino acid residues L1055-S1105.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64759
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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