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Invitrogen™ TEP1 Polyclonal Antibody
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Catalog No. PIPA520354
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100 μg
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Catalog No. Quantity
PIPA520354 100 μg
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Catalog No. PIPA520354 Supplier Invitrogen™ Supplier No. PA520354
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human kidney tissue lysate. PA5-20354 can be used with blocking peptide PEP-0474.

Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes. Besides the RNA component which serves as the template that specifies the telomeric repeat, the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TP1). Telomerase activity is low in most somatic cells, causing the gradual shortening of telomeres which can ultimately lead to telomere fusion and cell death. High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy, expression levels of TP1 do not correlate with malignancy. At least two isoforms of TP1 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TEP1
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene TEP1
Gene Accession No. O08653, P97499, Q99973
Gene Alias p230; p240; p80 homolog; p80 telomerase homolog; rTLP1; telomerase associated protein 1; telomerase protein 1; Telomerase protein component 1; telomerase-associated protein 1; Tep1; TLP1; Tp1; TROVE domain family, member 1; TROVE1; VAULT2
Gene Symbols TEP1
Host Species Rabbit
Immunogen A 20 amino acid peptide from near the amino terminus of human TP1.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21745, 64523, 7011
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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