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  5. Tocris Bioscience™ Terbinafine hydrochloride

Tocris Bioscience™ Terbinafine hydrochloride
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Catalog No. 648450
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Catalog No. Quantity
64-845-0 50 mg
64-842-50 250 mg
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Catalog No. 64-845-0 Supplier Tocris Bioscience™ Supplier No. 6484/50

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Description

Selective TASK3 activator

Terbinafine hydrochloride is a selective TASK3 activator (pEC50 = 6.2). Exhibits >10-fold selectivity for TASK3 over TREK2, TRESK, THIK1 and TASK2. Also inhibits TWIK1 (pIC50 = 5.69). Also antifungal; inhibits fungal sterol biosynthesis by inhibition of squalene epoxidase.

Specifications

CAS 78628-80-5
Synonym N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine hydrochloride
Quantity 50 mg
Molecular Formula C21H25N.HCl
Formula Weight 327.89
Purity 98%
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