Tocris Bioscience™ Teriflunomide
Dihydroorotate dehydrogenase inhibitor
Manufacturer: Tocris Bioscience™ 5069/50
DescriptionInhibitor of dihydroorotate dehydrogenase (Kd = 12 nM; Ki = 179 nM). Inhibits proliferation of mitogen- or cytokine-stimulated lymphoid cells in vitro by inhibiting cell cycle progression from G1 to S. Imunosuppressive agent. Active metabolite of leflunomide (Cat. No. 2228).
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