Invitrogen™ TESK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555558

Catalog No. PIPA555558

Description

Immunogen sequence: TLEEILSRLQ EEEQERDRKL QPTARGLLEK APGVKRLSSL DDKIPHKSPC PRRTIWLSRS QSDIFSRKPP RTVSVLDPYY RPRDGAARTP KVNPFSARQD LMGGKIKFFD LPSKSVISLV F Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 90%.

TESK2 or testis-specific kinase 2 is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. The kinase domain of TESK2 is structurally similar to the kinase domain of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). TESK2 is predominantly expressed in testis and prostate and plays an important role in spermatogenesis. TESK2 phosphorylates cofilin specifically at Ser-3 and induces formation of actin stress fibers and focal adhesions.

Specifications

• Antigen: TESK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TESK2
• Gene Alias: dual specificity testis-specific protein kinase 2; TESK2; Testicular protein kinase 2; testis-specific kinase 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10420
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.60 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96S53
• Gene Symbols: TESK2
• Immunogen: Recombinant protein corresponding to Human TESK2. Recombinant protein control fragment (Product #RP-89769).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov