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TESK2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982112
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50-198-2112 100 μL
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Catalog No. 50-198-2112 Supplier Bioss Supplier No. BS12293R
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Rabbit Polyclonal Antibody

TESK2 (testicular protein kinase 2) is a nuclear protein that belongs to the protein kinase superfamily and is expressed in testis and prostate. Functioning as a dual specificity protein kinase, TESK2 catalyzes the ATP-dependent phosphorylation of substrates and autophosphorylation on tyrosine and serine/ threonine residues, thereby mediating intracellular signal transduction pathways. TESK2 requires magnesium as a cofactor and its catalytic activity is thought to play an important role in meiotic events such as spermatogenesis.TESK2 contains one protein kinase domain that is 65% identical to the kinase domain found in TESK1 (testicular protein kinase 1), suggesting a similar role for these proteins in phosphorylation events. Three isoforms of TESK2 are expressed due to alternative splicing.

Specifications

Antigen TESK2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene TESK2
Gene Accession No. Q96S53
Gene Alias Dual specificity testis-specific protein kinase 2; Tesk2; Testicular protein kinase 2; testis-specific kinase 2
Gene Symbols TESK2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human TESK2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10420
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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