Invitrogen™ TESPA1 Polyclonal Antibody

Catalog No.	Quantity
FEPA5145202	100 μL

Catalog No. FEPA5145202 Supplier Invitrogen™ Supplier No. PA5145202

Description

Rabbit Polyclonal Antibody

Immunogen sequence: GTNKTSSSIS EILDKVQEDA EDVLFSLGFG QEDHKDTSRI PARFFTTPSQ AKGIDFQLFL KSQVRRIEME DPCLMLASRF KQVQTLAVT Antigen sequence identity: Mouse 90%; Rat 43%.

TESPA1 is a critical component of the TCR signalosome and is essential for T cell selection and maturation through the regulation of TCR signaling during T cell development. TESPA1 encodes a protein of 458 amino acids and is highly conserved among vertebrate species. TESPA1 expression was tightly regulated during T cell development, with highest expression at the DP stage. TESPA1 deficiency resulted in failure of positive selection and substantially fewer of CD4+ and CD8+ SP cells in the thymus.

Specifications

• Antigen: TESPA1
• Applications: Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.05 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: TESPA1
• Gene Accession No.: A2RU30
• Gene Alias: 5830405N20Rik; A430001F24Rik; AI450549; HSPC257; KIAA0748; LOW QUALITY PROTEIN: protein TESPA1; protein TESPA1; TESPA1; thymocyte expressed; thymocyte expressed, positive selection associated 1; thymocyte-expressed positive selection-associated protein 1
• Gene Symbols: TESPA1
• Host Species: Rabbit
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 142-230. Recombinant protein control fragment (Product #RP-110088).
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9840
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Format: Liquid
• Isotype: IgG