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TESPA1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735145 Shop All Proteintech Group Inc Products
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50-173-5145 150 μL
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Catalog No. 50-173-5145 Supplier Proteintech Group Inc Supplier No. 259751AP150UL
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Rabbit Polyclonal Antibody

TESPA1 is a critical component of the TCR signalosome and is essential for T cell selection and maturation through the regulation of TCR signaling during T cell development. TESPA1 encodes a protein of 458 amino acids and is highly conserved among vertebrate species. TESPA1 expression was tightly regulated during T cell development, with highest expression at the DP stage. TESPA1 deficiency resulted in failure of positive selection and substantially fewer of CD4+ and CD8+ SP cells in the thymus.

Specifications

Antigen TESPA1
Applications Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene TESPA1
Gene Accession No. A2RU30
Gene Alias HSPC257, KIAA0748, TESPA1
Gene Symbols TESPA1
Host Species Rabbit
Immunogen TESPA1 Fusion Protein Ag23218
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9840
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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