Invitrogen™ Tet Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144574

Catalog No. FEPA5144574

Description

Tet Polyclonal Antibody for Western Blot, ELISA

Dioxygenase that specifically demethylates DNA methylated on the 6th position of adenine (N(6)-methyladenosine) DNA (PubMed:25936838, PubMed:30078725). N(6)-methyladenosine (m6A) DNA is present at a relatively high level at the very earliest embryonic stages but at low levels at the late embryonic stages and may act as a regulator of gene expression (PubMed:25936838). Promotes differentiation of early germ cells in ovary (PubMed:25936838). Contributes to neuronal morphology, development, and function in the brain (PubMed:30078725). By interacting with histone modifier wds, binds to a specific set of genes, modulates intragenic (N(6)-methyladenosine) DNA levels and thereby maintains transcriptional activation (PubMed:30078725). Also able to catalyze the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) (PubMed:25936838).

Specifications

• Antigen: Tet
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tet
• Gene Alias: DMAD
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 38347
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.808 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
• Gene Accession No.: M9NEY8
• Gene Symbols: Tet
• Immunogen: Recombinant Fruit fly Tet protein (2494-2767aa).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Drosophila
• Product Type: Antibody
• Isotype: IgG