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TET1 Monoclonal Antibody (OTI7E2), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Supplier: OriGene TA802234
Description
Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.Specifications
| TET1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q8NFU7 | |
| TET1 | |
| Human recombit protein fragment corresponding to amino acids 1-305 of human TET1 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI7E2 | |
| Unconjugated | |
| TET1 | |
| CXXC6, LCX, bA119F7.1 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 80312 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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