TET1 Mouse anti-Human, Clone: OTI7E2, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-5917	100 μg

Catalog No. 50-166-5917 Supplier OriGene Supplier No. CF802234

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.

Specifications

• Antigen: TET1
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI7E2
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: TET1
• Gene Accession No.: Q8NFU7
• Gene Alias: CXXC6, LCX, bA119F7.1
• Gene Symbols: TET1
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-305 of human TET1 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 80312
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1