TET3 Mouse anti-Human, Clone: OTI2F10, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF803973

Catalog No. 50-166-6747

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid maligcies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.

Specifications

• Antigen: TET3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TET3
• Gene Alias: hCG_40738
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 200424
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI2F10
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: O43151
• Gene Symbols: TET3
• Immunogen: Human recombit protein fragment corresponding to amino acids 241-568 of human TET3 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1