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Invitrogen™ TET3 Polyclonal Antibody
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Catalog No. PIPA596735
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100 μL
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PIPA596735 100 μL
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Catalog No. PIPA596735 Supplier Invitrogen™ Supplier No. PA596735
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Description

Rabbit Polyclonal Antibody

Positive Samples: Jurkat, HT-29, SKOV3, Mouse lung, Rat thymus; Cellular Location: Cytoplasm, Nucleus Immunogen sequence: GFQDKLWNPM KGEEGRIPAA GASQLDRAWQ SFGLPLGSSE KLFGALKSEE KLWDPFSLEE GPAEEPPSKG AVKEEKGGGG AEEEEEELWS DSEHNFLDEN.

TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TET3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 0.69 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TET3
Gene Accession No. O43151, Q8BG87
Gene Alias B430006D22Rik; BC037432; D230004J03Rik; hCG_40738; KIAA0401; Methylcytosine dioxygenase TET3; MGC22014; probable methylcytosine dioxygenase TET3; putative methylcytosine dioxygenase; Tet methylcytosine deoxygenase 3 isoform; tet methylcytosine dioxygenase 3; tet oncogene family member 3; Tet3
Gene Symbols TET3
Host Species Rabbit
Immunogen Recombinant protein (or fragment)
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 194388, 200424, 680576
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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