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TET3 Polyclonal Antibody, Rockland™
SDP

Catalog No. 501990141
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100 μL
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50-199-0141 100 μL
50-199-0142 25 μL
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Catalog No. 50-199-0141 Supplier Rockland Immunochemicals Supplier No. 100401N94
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Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. It is directed against, and shows specific reactivity for Tet3 protein. Cross reactivity with Tet1 and Tet2 has not been determined.

TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.

Specifications

Antigen TET3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 70 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene TET3
Gene Accession No. O43151
Gene Alias B430006D22Rik; BC037432; D230004J03Rik; hCG_40738; KIAA0401; Methylcytosine dioxygenase TET3; MGC22014; probable methylcytosine dioxygenase TET3; putative methylcytosine dioxygenase; Tet methylcytosine deoxygenase 3 isoform; tet methylcytosine dioxygenase 3; tet oncogene family member 3; Tet3
Gene Symbols TET3
Host Species Rabbit
Immunogen TET3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a human TET-3 domain containing the N-terminal 160 amino acids of the protein.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 200424
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
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