Invitrogen™ TFB2M Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA583135

Catalog No. PIPA583135

Description

Immunogen sequence: FKNLGIEAVP WTADIPLKVV GMFPSRGEKR ALWKLAYDLY SCTSIYKFGR IEVNMFIGEK EFQKLMADPG NPDLYHVLSV IWQLACEIK.

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.

Specifications

• Antigen: TFB2M
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tfb2m
• Gene Alias: dimethyladenosine transferase 2, mitochondrial; FLJ22661; FLJ23182; HCV NS5A-transactivated protein 5; Hepatitis C virus NS5A-transactivated protein 5; Hkp1; h-mtTFB; h-mtTFB2; house-keeping protein 1; hTFB2M; mitochondrial 12S rRNA dimethylase 2; Mitochondrial transcription factor B2; mTFB2M; mtTFB2; NS5ATP5; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2; TFB2M; transcription factor B2, mitochondrial
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64216
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H5Q4
• Gene Symbols: Tfb2m
• Immunogen: Recombinant protein corresponding to Human TFB2M. Recombinant protein control fragment (Product #RP-94418).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG