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Invitrogen™ TFB2M Polyclonal Antibody
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Catalog No. PIPA583135
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100 μL
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Catalog No. Quantity
PIPA583135 100 μL
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Catalog No. PIPA583135 Supplier Invitrogen™ Supplier No. PA583135
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FKNLGIEAVP WTADIPLKVV GMFPSRGEKR ALWKLAYDLY SCTSIYKFGR IEVNMFIGEK EFQKLMADPG NPDLYHVLSV IWQLACEIK Highest antigen sequence indentity to the following orthologs: Mouse - 60%, Rat - 64%.

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TFB2M
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Tfb2m
Gene Accession No. Q9H5Q4
Gene Alias dimethyladenosine transferase 2, mitochondrial; FLJ22661; FLJ23182; HCV NS5A-transactivated protein 5; Hepatitis C virus NS5A-transactivated protein 5; Hkp1; h-mtTFB; h-mtTFB2; house-keeping protein 1; hTFB2M; mitochondrial 12S rRNA dimethylase 2; Mitochondrial transcription factor B2; mTFB2M; mtTFB2; NS5ATP5; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2; TFB2M; transcription factor B2, mitochondrial
Gene Symbols Tfb2m
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TFB2M. Recombinant protein control fragment (Product #RP-94418).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64216
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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