Tocris™ TFC 007

Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor

Manufacturer: Tocris™ 5108/50

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Catalog No. 51-085-0

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For Research Use Only


    Product Type TFC 007
    Inhibitors TFC 007
    Purity >98
    Molecular Weight 487.55
    Quantity 50mg

    Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor (IC50 = 83nM). Inhibits PGD2 production and late phase nasal blockage in an animal model of allergic rhinitis. Exhibits negligible effects on COX-1, COX-2, 5-LOX, LTC4 synthase, TXA2 synthase and microsomal prostaglandin E2 synthase.

    • Chemical Name: N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide
    • Formula: C27H29N5O4
    • CAS Number: 927878-49-7
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98
  • Description & Specifications

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