Invitrogen™ TFE3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101090

Catalog No. PIPA5101090

Description

Antibody detects endogenous levels of total TFE3.

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

Specifications

• Antigen: TFE3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TFE3
• Gene Alias: bHLHe33; Class E basic helix-loop-helix protein 33; F830016E06Rik; RCCP2; RCCX1; RGD1559642; Tcfe3; TFE3; Tfe-3; TFEA; transcription factor binding to IGHM enhancer 3; transcription factor E family, member A; transcription factor E3; transcription factor for IgH enhancer; transcription factor for immunoglobulin heavy-chain enhancer 3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 209446, 7030
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P19532, Q64092
• Gene Symbols: TFE3
• Immunogen: A synthesized peptide derived from human TFE3(Accession P19532), corresponding to amino acid residues T103-S153.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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