Invitrogen™ TFEB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534360

Catalog No. PIPA534360

Description

A suggested positive control is A549 cell lysate. PA5-34360 can be used with blocking peptide PEP-1403.

The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1. Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.

Specifications

• Antigen: TFEB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TFEB
• Gene Alias: Alpha TCFEB; ALPHATFEB; BHLHE35; Class E basic helix-loop-helix protein 35; RP4-696P19.3; T-cell transcription factor EB; Tcfeb; Tfeb; Transcription factor EB
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7942
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P19484
• Gene Symbols: TFEB
• Immunogen: An 18 amino acid synthetic peptide near the amino terminus of human TFEB.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov