Invitrogen™ TFEB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA586738

Catalog No. PIPA586738

Description

Purity is > 95% by SDS-PAGE.

The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1. Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.

Specifications

• Antigen: TFEB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TFEB
• Gene Alias: Alpha TCFEB; ALPHATFEB; BHLHE35; Class E basic helix-loop-helix protein 35; RP4-696P19.3; T-cell transcription factor EB; Tcfeb; Tfeb; Transcription factor EB
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21425, 316214, 7942
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P19484, Q9R210
• Gene Symbols: TFEB
• Immunogen: Synthetic peptide, corresponding to amino acids 6-51 of Human TFEB.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov