TFEB Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-559-233	Proteintech Group Inc 133721AP150UL	150 μL

Description

This is a rabbit polyclonal antibody raised against the full length of human TFEB. The calculated molecular weight of TFEB is 53 kDa, but modified TFEB is about 65-70 kDa.

The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1. Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.

Specifications

• Antigen: TFEB
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P19484, Q9R210
• Gene ID (Entrez): 21425, 316214, 7942
• Immunogen: TFEB Fusion Protein Ag4194
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: TFEB

• Concentration: 0.35 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: AlphaTFEB, bHLHe35, TCFEB, TFEB, transcription factor EB
• Gene Symbols: Tfeb
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody