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  6. Invitrogen™ TFF2 Monoclonal Antibody (1-2#)

Invitrogen™ TFF2 Monoclonal Antibody (1-2#)
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Catalog No. PIMA541684
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Quantity:
20 μL
200 μL
Catalog No. Quantity
PIMA541684 200 μL
PIMA543561 20 μL
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Catalog No. PIMA541684

Supplier: Invitrogen™ MA541684

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Description

Mouse Monoclonal Antibody

TFF2 Monoclonal Antibody for Western Blot, IHC (P)

Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. SP (spasmolytic polypeptide), also designated Trefoil factor 2 (TFF2) precursor, is a trefoil protein that functions to inhibit gastrointestinal motility and gastric acid secretion. SP may also act as a structural component of the gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. A downregulation of SP expression is associated with primary gastric cancer, and a progressive loss of this protein is likely to be involved in the early stage of the multi-step gastric carcinogenesis pathway.
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Specifications

Antigen TFF2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1-2#
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene Tff2
Gene Accession No. Q09030
Gene Alias mSP; pancreatic spasmolytic polypeptide; PSP; SML1; SP; spasmolysin; Spasmolytic polypeptide; spasmolytic protein 1; Tff2; Trefoil factor 2; trefoil factor 2 (spasmolytic protein 1)
Gene Symbols Tff2
Host Species Mouse
Immunogen Recombinant protein Trefoil Factor 2. The antigen corresponds to amino acid range 27-129 of the target protein.
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116592
Target Species Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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