TFF2 Mouse anti-Human, Porcine, Rat, Clone: 2D7B1, Proteintech

Catalog No.	Quantity
50-173-6894	150 μL

Catalog No. 50-173-6894 Supplier Proteintech Group Inc Supplier No. 664711IG150UL

Description

Mouse Monoclonal Antibody

Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. SP (spasmolytic polypeptide), also designated Trefoil factor 2 (TFF2) precursor, is a trefoil protein that functions to inhibit gastrointestinal motility and gastric acid secretion. SP may also act as a structural component of the gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. A downregulation of SP expression is associated with primary gastric cancer, and a progressive loss of this protein is likely to be involved in the early stage of the multi-step gastric carcinogenesis pathway.

Specifications

• Antigen: TFF2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 2D7B1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: TFF2
• Gene Accession No.: P01359, Q03403, Q09030
• Gene Alias: SML1, SP, Spasmolysin, Spasmolytic polypeptide, TFF2, trefoil factor 2
• Gene Symbols: TFF2
• Host Species: Mouse
• Immunogen: TFF2 Fusion Protein Ag18765
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 116592, 397420, 7032
• Target Species: Human, Pig, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a