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TFF2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 50559853 Shop All Proteintech Group Inc Products
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50-559-853 150 μL
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Catalog No. 50-559-853 Supplier Proteintech Group Inc Supplier No. 136811AP150UL
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Description

Rabbit Polyclonal Antibody

Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. SP (spasmolytic polypeptide), also designated Trefoil factor 2 (TFF2) precursor, is a trefoil protein that functions to inhibit gastrointestinal motility and gastric acid secretion. SP may also act as a structural component of the gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. A downregulation of SP expression is associated with primary gastric cancer, and a progressive loss of this protein is likely to be involved in the early stage of the multi-step gastric carcinogenesis pathway.

Specifications

Antigen TFF2
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TFF2
Gene Accession No. Q03403, Q03404
Gene Alias SML1, SP, Spasmolysin, Spasmolytic polypeptide, TFF2, trefoil factor 2
Gene Symbols TFF2
Host Species Rabbit
Immunogen TFF2 Fusion Protein Ag4537
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21785, 7032
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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