TFF3 Mouse anti-Human, Clone: OTI4D10, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF811447

Catalog No. 50-167-0654

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. Trefoil peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain and are clustered in human chromosome 21q22.3. Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells that line mucus membranes in the large and small intestines and lower respiratory tract. TFF3 is mainly active as a disulfide-linked homodimer and may have a role in promoting cell migration in healing processes. It is involved in the maintece and repair of the intestinal mucosa.

Specifications

• Antigen: TFF3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TFF3
• Gene Alias: ITF, P1B, TFI
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7033
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4D10
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q07654
• Gene Symbols: TFF3
• Immunogen: Human recombit protein fragment corresponding to amino acids 72-130 of human TFF3 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1